Prof. Terry Hébert from McGill University will discuss “Assessing Bias and Allostery in GPCRs using Conformational Biosensors” at GTCbio’s GPCR in Drug Discovery Conference in Boston, MA

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Ligand-biased signaling could have a significant impact on drug discovery programs in the pharmaceutical industry. As such, many investigators and screening campaigns are now being directed at a larger section of the signaling responses downstream of an individual G protein-coupled receptor. Biosensor-based platforms have been developed to capture signaling signatures. Despite the ability to use […]

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Kevin Morris, from the City of Hope, to discuss “Genomic Dark Matter; The Complexities of Non-Coding RNA from Mechanism to Therapeutics” at 7th Non-Coding RNA & RNAi Therapeutics Conference

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Observations over the past decade have demonstrated that exogenously introduced non-coding RNAs can transcriptionally modulate gene expression in human cells by recruiting silent state epigenetic marks to target loci. Dr. Kevin Morris will present evidence here suggesting that long non-coding RNAs (lncRNAs), which are antisense to particular protein-coding genes, function in human cells as effector […]

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Erin Keaney, Novartis, will give a presentation at 11th Drug Design & Medicinal Chemistry (September 12-13, 2016 in Boston, MA)

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The autophagy process is an essential pathway utilized by cells to breakdown damaged cellular constituents and provide the cell with energy. A variety of diseases including cancer and neurodegeneration have been linked to the activation or inhibition of autophagy. In an effort to identify pharmacological agents to inhibit this process, Dr. Keaney’s group utilized a […]

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Richard Buller, VP at Pfizer, to Give a Keynote at GTCbio’s Biomarker Summit Europe 2016

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Richard E. Buller, Vice President of Oncology, Clinical Development & Head of Global Product Development at Pfizer will give a keynote presentation on, “Feedback Loops Between Biomarkers and Targeted Agents in Clinical Trials and Beyond: Lessons from Anaplastic Lymphoma Kinase (ALK+) Driven Non-Small Cell Lung Cancer (NSCLC)“ at GTCbio’s Biomarker Summit Europe 2016 to be […]

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Diana Colleluori from Bluebird Bio will present, “Quality Control Considerations for Commercialization of Autologous Cell Products” at 3rd Cell & Gene Therapy (Sept, 12-13, 2016 in Boston, MA)

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Quality expectations are not based on the speed of the approval process, thus leading to quality control challenges in expedited product development cycles as exists for gene therapies.  Most often, there is less product information and limited data available at the time of marketing submissions.  Sponsors are faced with overcoming many quality challenges, including analytical […]

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CNS Diseases World Summit- September 12-15, 2016 in Boston.

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We are excited to announce the CNS Diseases World Summit, to be held on September 12-15, 2016 in Boston, MA. This meeting provides an interactive learning and relationship-building forum for all players in the CNS field. Colleagues from industry, academia, government agencies, and financing bodies will gather at the interface of research, partnerships, funding, and commercialization to find […]

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Lee E. Walko from Omni Tech International will give a Speak at the 7th Biobased Chemicals Commercialization & Partnering Conference (July 7-8, 2016, Boston)

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Lee E. Walko, Biobased Business Development Manager at Omni Tech International, will give a talk titled, “The Need for Speed,” at GTCbio’s 7th Biobased Chemicals Commercialization & Partnering Conference to be held on July 7-8, 2016 in Boston, MA.   Omni Tech and Biobased Global have teamed up to focus on applying lean startup techniques […]

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Robert Weinberg, Daniel K. Ludwig Professor for Cancer Research at MIT to present at 2nd Cancer Markers & Liquid Biopsies (July 6-7, 2016 in Boston MA)

Robert Weinberg, Daniel K. Ludwig Professor for Cancer Research at MIT, will give a presentation, on “Mechanisms of Malignant Progression of Carcinomas” at GTCbio’s 2nd Cancer Markers & Liquid Biopsies Conference to be held on July 6-7, 2016 in Boston, MA. Carcinoma cells within primary tumors activate a previously latent cell-biological program termed the epithelial-mesenchymal transition (EMT), […]

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